Powering biologists’s minds to make discoveries.

Web applications can finally handle genome-scale biological data. Even your iPhone does on-the-fly machine learning.

Point and click analysis for transcriptomics/differential expression.

Dropbox has drag-and-drop interaction. Suddenly, it makes sense for science too.

The modern era, but biology is still catching up.

The standard for search suggestion & results

People still used Internet Explorer—for real.

Barely one year into Obama’s first term. People were listening to Rihanna sing about finding love in a hopeless place. The iPhone 3GS was the hottest thing.

Web 2.0 is still pretty new, but animation, interactivity, and more data are coming to even the previously static Google Search UI.

Google Chrome hadn’t yet come out, Web 2.0 was still a thing. Android was brand new.

Google plays a huge role in public emergencies, like pandemics. We worked with HHS to provide public health guidance and to direct people to resources like flu vaccine clinics

As if the financial crisis wasn’t enough, here was a potentially serious pandemic.

The era of ”Big Data,” and just getting a handle on how to structure it.

Empowering people to find what works, faster

People were listening on their iPhone 6 to Hotline Bling.

Portable tech was coming of age—it was the year of the Apple Watch.

Folks might have been dancing to Happy by Pharrell Williams.

A new standard for open public health data

Governments were just starting to adopt modern technologies, and yes, we still had to support Internet Explorer.

The authoritative source on Mac user interface design.

Apple just released the iPod. Google just got out of beta. If you had a cell phone at all, it was a flip phone.

A lot of software still came in boxes—on a CD.

## **Depression treatment is broken.** We built Start to fill in one of the gaps: medication follow-up.

## **Few people get the attention they need when starting an antidepressant.** We built Start to fill in the gap, give people control, and help them find their way to something that works.

![Alt](/content/projects/start/p_startOnPhone.jpg)

The first line of depression treatment in primary care—antidepressants—work at best about 1/3 of the time. Millions of Americans are prescribed these medicines but don’t get the follow-up they need to find out whether theirs works for them.

![Alt](/content/projects/start/p_startCheckIn.png)

Start brought a clarity to the trial and error of this aspect of depression treatment and accelerated the trial and error process according to accepted best medical practices. It guided people through the initial period of adjustment to the medication, and providing actionable context at critical times about whether the medication and other treatment efforts are working. Apple recognized the app and we were a CareKit launch partner.

![Alt](/content/projects/start/p_startProgress.png)

People with depression can find themselves in a fog, ruminating on negative thoughts, and struggling to see a path towards improvement. Start is designed for minimal interaction—just enough to help people take action. It provides pharmacist guidance about what to expect, daily tips, and optional pill reminders. Data collection is sparse—just every couple of days. No "daily dashboard" is provided; instead, a Start user gets a bi-weekly progress report that carefully reflects back and contextualizes the person’s experience in research about evaluating and making treatment decisions. These are explicitly designed to be useful both to them and their clinicians, with whom they can easily share the report. 

![Alt](/content/projects/start/p_explainer1.jpg)

I turned research with our iodine.com users on their latent needs into this project, conceiving of its program from scratch, gathered evidence to support the mission, and guided product development. Michael Schultz and Ross Patton did terrific design work and Marc Mendiola and Hans Nelson built the majority of the key parts of the app. 

![Alt](/content/projects/start/p_explainer2.jpg)

Depression treatment is broken. We built Start to fill in one of the gaps: medication follow-up.

Start